Hmg Coa Reductase Inhibitors Pptx
Hmg Coa Reductase Inhibitors Pptx The document provides examples of prodrug linkages and enzymes involved in their hydrolysis. this presentation discusses hmg coa reductase inhibitors, also known as statins. it begins with an introduction to hyperlipidemia and its risk factors. it then discusses atorvastatin as the prototype statin drug, and provides examples of other statins. Hmg co a reductase inhibitors. this document discusses statins, which are medications that lower cholesterol by inhibiting hmg coa reductase. statins are the most effective treatment for hyperlipidemia and cardiovascular disease. they work by decreasing cholesterol synthesis in the liver and increasing ldl receptors to clear ldl cholesterol.
Hmg Coa Reductase Inhibitors Pptx 2. what is statin? statins (or hmg coa reductase inhibitors) are a class of drugs used to lower cholesterol levels by inhibiting the enzyme hmg coa reductase, which plays a central role in the production of cholesterol in the liver, which produces about 70 percent of total cholesterol in the body. Hmg coa reductase inhibitors (statins) are lipid lowering medications used in the primary and secondary prevention of coronary heart disease. this activity reviews the indications, contraindications, and mechanism of action of statins for the management of coronary heart disease and familial dyslipidemias. this activity will cover the indications, contraindications, activity, adverse events. Presentation transcript. lipid lowering agents by: dr israa omar mbbs, mrcp, msc pharmacology. hmg coa reductase inhibitors • reduces plasma concentration of ldl cholestrol by more than 30%. • also cause a small reduction on plasma tga and a small increase in plasma hdl • (statins)include simvastatin, pravastatin, atorvastatin. 10. indications for intervention hypertriglyceridemi. a. base initial management on lifestyle and dietary. modification. consider lipid lowering agents (gt 1000 mg dl) in. absence of other risk factors. consider lipid lowering agents at lower levels (gt. 500 mg dl) if other risks are present.
Hmg Coa Reductase Inhibitors Pptx Presentation transcript. lipid lowering agents by: dr israa omar mbbs, mrcp, msc pharmacology. hmg coa reductase inhibitors • reduces plasma concentration of ldl cholestrol by more than 30%. • also cause a small reduction on plasma tga and a small increase in plasma hdl • (statins)include simvastatin, pravastatin, atorvastatin. 10. indications for intervention hypertriglyceridemi. a. base initial management on lifestyle and dietary. modification. consider lipid lowering agents (gt 1000 mg dl) in. absence of other risk factors. consider lipid lowering agents at lower levels (gt. 500 mg dl) if other risks are present. Hmg coa reductase inhibitors statins and fixed dose combination products containing a statin update 6: preliminary sc inclusion criteria. individual statins:atorvastatin, fluvastatin, fluvastain extended release, lovastatin, lovastatin extended release, pravastatin, rosuvastatin, simvastatinfixed dose combination products:lovastatin niacin. Excerpt. hmg coa reductase inhibitors (statins) are lipid lowering medications used in the primary and secondary prevention of coronary heart disease. this activity reviews the indications, contraindications, and mechanism of action of statins for the management of coronary heart disease and familial dyslipidemias.
Hmg Coa Reductase Inhibitors Pptx Hmg coa reductase inhibitors statins and fixed dose combination products containing a statin update 6: preliminary sc inclusion criteria. individual statins:atorvastatin, fluvastatin, fluvastain extended release, lovastatin, lovastatin extended release, pravastatin, rosuvastatin, simvastatinfixed dose combination products:lovastatin niacin. Excerpt. hmg coa reductase inhibitors (statins) are lipid lowering medications used in the primary and secondary prevention of coronary heart disease. this activity reviews the indications, contraindications, and mechanism of action of statins for the management of coronary heart disease and familial dyslipidemias.
Hmg Coa Reductase Inhibitors Pptx
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