Figure 1 From Impact Of Three Commonly Used Blood Sampling Techniques

Figure 1 From Impact Of Three Commonly Used Blood Sampling Techniques Laboratory mice are the most frequently used animals in biomedical research. in accordance with guidelines for humane handling, several blood sampling techniques have been established. while the effects of these procedures on blood quality and histological alterations at the sampling site are well studied, their impact on the animals’ welfare has not been extensively investigated. therefore. Impact of three commonly used blood sampling techniques on the welfare of laboratory mice: taking the animal’s perspective neele meyer id 1*, mareike kro¨ ger , julia thu¨ mmler2, lisa tietze2, rupert palme3, chadi touma1* 1 department of behavioural biology, university of osnabru¨ ck, osnabrueck, germany, 2 research group of.

Table 1 From Impact Of Three Commonly Used Blood Sampling Techniques On Schematic timeline of the four experiments. male c57bl 6j mice were investigated in four different experiments (a d). the treatment comprises one of the three blood sampling techniques (tail. Fig 1. schematic timeline of the four experiments. male c57bl 6j mice were investigated in four different experiments (a–d). the treatment comprises one of the three blood sampling techniques (tail vessel bleeding (tvb), retrobulbar bleeding (rbb) or facial vein bleeding (fvb)) or one of the two control treatments (handling control (hco) or anaesthesia control (aco)). (a) in experiment 1. Laboratory mice are by far the most widely used vertebrate species in biomedical research [ 1 ]. in this research domain, it is often necessary to collect blood samples. yet, blood sampling in mice potentially causes distress and could impact the health and welfare of the experimental animal and might bias the obtained results. Compared three commonly used blood sampling techniques regarding their effects on different indicators of animal welfare, including physiological and behavioural response stress parameters, to allow researchers to objectively select the most appropriate and welfare friendly blood sampling technique for a given experiment. laboratory mice are the most frequently used animals in biomedical.

Pdf Impact Of Three Commonly Used Blood Sampling Techniques On The Laboratory mice are by far the most widely used vertebrate species in biomedical research [ 1 ]. in this research domain, it is often necessary to collect blood samples. yet, blood sampling in mice potentially causes distress and could impact the health and welfare of the experimental animal and might bias the obtained results. Compared three commonly used blood sampling techniques regarding their effects on different indicators of animal welfare, including physiological and behavioural response stress parameters, to allow researchers to objectively select the most appropriate and welfare friendly blood sampling technique for a given experiment. laboratory mice are the most frequently used animals in biomedical. Impact of three commonly used blood sampling techniques on the welfare of laboratory mice: taking the animal’s perspective. plos one 15(9), e0238895. laboratory mice are the most frequently used animals in biomedical research. After intravenous injection of 1 and 15 mg kg of rfviia in fviii knockout mice, a dose dependent increase in the plasma level of fviia activity was observed in both blood collection techniques (figure 1). two additional blood samples were successfully collected over a period of 60 min. during this period, the fviia activity in plasma gradually.

Impact Of Three Commonly Used Blood Sampling Techniques On The Welfare Impact of three commonly used blood sampling techniques on the welfare of laboratory mice: taking the animal’s perspective. plos one 15(9), e0238895. laboratory mice are the most frequently used animals in biomedical research. After intravenous injection of 1 and 15 mg kg of rfviia in fviii knockout mice, a dose dependent increase in the plasma level of fviia activity was observed in both blood collection techniques (figure 1). two additional blood samples were successfully collected over a period of 60 min. during this period, the fviia activity in plasma gradually.